The Dutch facility for electron microscopy with the most advanced cryo-transmission electron microscopes available worldwide

Our Services

Electron Microscopy

NeCEN is an open access facility for high resolution cryo-electron microscopy of biological samples. Two state-of-the-art Titan Krios transmission electron microscopes allow cost-efficient automated data collection for our customers.

Sample preparation

Flash freezing enables preservation of biological samples in a vitrified, close-to-native state. The cryo lab at NeCEN is equipped with all instrumentation needed to prepare samples for atomic resolution data collection.

Data processing

No high resolution structure is possible without data processing. The experienced operators at NeCEN help you on-site to get most out of your data using state-of-the-art hardware and software.


Want to know it all? Intense training courses at NeCEN will make you a cryo-EM expert! 


Due to the Covid-19 pandemic the dates of the next Cryo-EM school sessions have yet to be determined. Please don't hesitate to contact us if you are interested.

“Having access to modern cryo-EM infrastructure is essential for small working groups like mine because it allows us to collect high-resolution datasets and contribute to a rapidly advancing structural biology field. Accordingly, NECEN and the iNext program, which covers associated access costs, fulfil an important role in European science by providing rapid access to state-of-the-art infrastructure and extremely knowledgeable staff that maximize the quality of collected data and thus ensure the best possible foundation for successful structural determination.”

- Sean Connell, CIC BioGUNE, Derio, Spain

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NeCEN is a dedicated facility for cryo-electron microscopy with two of the most advanced cryo-transmission electron microscopes available worldwide to collect the best possible data for single particle analysis and electron tomography.